diff --git a/packages/wxt/vitest.config.ts b/packages/wxt/vitest.config.ts
index e22c7f0c..8bb1d0da 100644
--- a/packages/wxt/vitest.config.ts
+++ b/packages/wxt/vitest.config.ts
@@ -6,12 +6,12 @@ export default defineConfig({
   test: {
     mockReset: true,
     restoreMocks: true,
-    setupFiles: ['vitest.setup.ts'],
     testTimeout: 120e3,
     coverage: {
       include: ['src/**'],
       exclude: ['**/dist', '**/__tests__', 'src/utils/testing'],
     },
+    globalSetup: ['./vitest.globalSetup.ts'],
   },
   server: {
     watch: {
diff --git a/packages/wxt/vitest.globalSetup.ts b/packages/wxt/vitest.globalSetup.ts
new file mode 100644
index 00000000..3847f26a
--- /dev/null
+++ b/packages/wxt/vitest.globalSetup.ts
@@ -0,0 +1,19 @@
+import { exists, rm } from 'fs-extra';
+
+let setupHappened = false;
+
+export async function setup() {
+  if (setupHappened) {
+    throw new Error('setup called twice');
+  }
+
+  setupHappened = true;
+
+  // @ts-expect-error
+  globalThis.__ENTRYPOINT__ = 'test';
+
+  const e2eDistPath = './e2e/dist/';
+  if (await exists(e2eDistPath)) {
+    await rm(e2eDistPath, { recursive: true, force: true });
+  }
+}
diff --git a/packages/wxt/vitest.setup.ts b/packages/wxt/vitest.setup.ts
deleted file mode 100644
index f5a0d17a..00000000
--- a/packages/wxt/vitest.setup.ts
+++ /dev/null
@@ -1,2 +0,0 @@
-// @ts-expect-error
-globalThis.__ENTRYPOINT__ = 'test';